STUB1

GENE INFORMATION

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Gene name

STUB1 (HGNC Symbol)

Synonyms

CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1

Description

STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2. [provided by RefSeq, Jun 2014]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

730224 - 732870

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103266 (version 75.37)

Entrez gene

10273

UniProt

Q9UNE7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UNE7

Antibodypedia

STUB1 antibodies
 

PROTEIN VIEW

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STUB1-001
 
STUB1-002
 
STUB1-004
 
STUB1-008
 
STUB1-010
 
STUB1-011
 
STUB1-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STUB1-001 ENSP00000219548
ENST00000219548
Q9UNE7
Show all »
Show » Show » 303 34.9 No 0
STUB1-002 ENSP00000457228
ENST00000565677
Q9UNE7
Show all »
Show » Show » 231 27.1 No 0
STUB1-004 ENSP00000456591
ENST00000567173
H3BS86
Show all »
Show » Show » 214 24.5 No 0
STUB1-008 ENSP00000456875
ENST00000564370
Q9UNE7
Show all »
Show » Show » 231 27.1 No 0
STUB1-010 ENSP00000457583
ENST00000566408
Show » Show » 185 21.4 No 0
STUB1-011 ENSP00000457090
ENST00000564316
Show » Show » 157 18.4 No 0
STUB1-012 ENSP00000476751
ENST00000565813
Show » 24 2.7 No 0