COPE

GENE INFORMATION

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Gene name

COPE (HGNC Symbol)

Synonyms

epsilon-COP

Description

Coatomer protein complex, subunit epsilon (HGNC Symbol)

Entrez gene summary

The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.11

Chromosome location (bp)

19010323 - 19030206

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105669 (version 75.37)

Entrez gene

11316

UniProt

O14579 (UniProt - Evidence at protein level)

neXtProt

NX_O14579

Antibodypedia

COPE antibodies
 

PROTEIN VIEW

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COPE-001
 
COPE-002
 
COPE-004
 
COPE-005
 
COPE-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COPE-001 ENSP00000262812
ENST00000262812
O14579
Show all »
Show » Show » 308 34.5 No 0
COPE-002 ENSP00000345674
ENST00000351079
O14579
Show all »
Show » Show » 257 28.8 No 0
COPE-004 ENSP00000469035
ENST00000600932
M0QXB4
Show all »
Show » Show » 331 36.9 No 0
COPE-005 ENSP00000343134
ENST00000349893
O14579
Show all »
Show » Show » 256 28.8 No 0
COPE-008 ENSP00000471034
ENST00000593827
M0R061
Show all »
Show » Show » 146 16.5 No 0