MEST

GENE INFORMATION

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Gene name

MEST (HGNC Symbol)

Synonyms

PEG1

Description

Mesoderm specific transcript (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]

Chromosome

7

Cytoband

q32.2

Chromosome location (bp)

130126012 - 130146133

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106484 (version 75.37)

Entrez gene

4232

UniProt

Q5EB52 (UniProt - Evidence at transcript level)

neXtProt

NX_Q5EB52

Antibodypedia

MEST antibodies
 

PROTEIN VIEW

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 « 
 
MEST-001
 
MEST-002
 
MEST-003
 
MEST-004
 
MEST-005
 
MEST-006
 
MEST-007
 
MEST-008
 
MEST-009
 
MEST-011
 
MEST-012
 
MEST-017
 
MEST-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MEST-001 ENSP00000223215
ENST00000223215
Q5EB52
Show all »
Show » Show » 335 38.8 No 0
MEST-002 ENSP00000342749
ENST00000341441
Q5EB52
Show all »
Show » Show » 326 37.6 Yes 0
MEST-003 ENSP00000408933
ENST00000416162
Q5EB52
Show all »
Show » Show » 292 33.8 Yes 0
MEST-004 ENSP00000367839
ENST00000378576
Q5EB52
Show all »
Show » Show » 292 33.8 Yes 0
MEST-005 ENSP00000401657
ENST00000437945
C9JW74
Show all »
Show » Show » 296 34.3 No 0
MEST-006 ENSP00000409505
ENST00000427521
C9JSW2
Show all »
Show » Show » 232 26.7 Yes 0
MEST-007 ENSP00000390589
ENST00000399874
C9JG66
Show all »
Show » Show » 118 13.6 Yes 0
MEST-008 ENSP00000409768
ENST00000433159
C9JRA9
Show all »
Show » Show » 160 18.5 Yes 0
MEST-009 ENSP00000407222
ENST00000421001
C9JWU9
Show all »
Show » Show » 207 23.7 Yes 0
MEST-011 ENSP00000393709
ENST00000437637
C9JUD2
Show all »
Show » Show » 127 14.6 Yes 0
MEST-012 ENSP00000396504
ENST00000458161
C9JCM6
Show all »
Show » Show » 169 19.5 Yes 0
MEST-017 ENSP00000473492
ENST00000463263
R4GN52
Show all »
Show » 173 20.1 No 0
MEST-201 ENSP00000376884
ENST00000393187
Q5EB52
Show all »
Show » Show » 326 37.6 Yes 0