KDM4C

GENE INFORMATION

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Gene name

KDM4C (HGNC Symbol)

Synonyms

GASC1, JMJD2C, KIAA0780, TDRD14C

Description

Lysine (K)-specific demethylase 4C (HGNC Symbol)

Entrez gene summary

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Chromosome

9

Cytoband

p24.1

Chromosome location (bp)

6720863 - 7175648

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107077 (version 75.37)

Entrez gene

23081

UniProt

Q9H3R0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H3R0

Antibodypedia

KDM4C antibodies
 

PROTEIN VIEW

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KDM4C-001
 
KDM4C-002
 
KDM4C-006
 
KDM4C-010
 
KDM4C-011
 
KDM4C-201
 
KDM4C-202
 
KDM4C-203
 
KDM4C-204
 
KDM4C-205
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KDM4C-001 ENSP00000370710
ENST00000381309
Q9H3R0
Show all »
Show » Show » 1056 120 No 0
KDM4C-002 ENSP00000370707
ENST00000381306
Q9H3R0
Show all »
Show » Show » 1047 118.4 No 0
KDM4C-006 ENSP00000400127
ENST00000420847
Show » Show » 354 39.5 No 0
KDM4C-010 ENSP00000383990
ENST00000401787
B0QZ60
Show all »
Show » 151 17.6 No 0
KDM4C-011 ENSP00000404756
ENST00000438023
F8WCN1
Show all »
Show » Show » 373 43.4 No 0
KDM4C-201 ENSP00000405739
ENST00000428870
C9J879
Show all »
Show » Show » 743 83.9 No 0
KDM4C-202 ENSP00000409353
ENST00000442236
E7EV17
Show all »
Show » Show » 801 91.2 No 0
KDM4C-203 ENSP00000442382
ENST00000535193
Q9H3R0
Show all »
Show » Show » 835 94.4 No 0
KDM4C-204 ENSP00000440656
ENST00000536108
F5GYH2
Show all »
Show » Show » 629 70.2 No 0
KDM4C-205 ENSP00000445427
ENST00000543771
Q9H3R0
Show all »
Show » Show » 813 91.9 No 0