APBA1

GENE INFORMATION

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Gene name

APBA1 (HGNC Symbol)

Synonyms

D9S411E, MINT1, X11

Description

Amyloid beta (A4) precursor protein-binding, family A, member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q21.11

Chromosome location (bp)

72042446 - 72287222

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107282 (version 75.37)

Entrez gene

320

UniProt

Q02410 (UniProt - Evidence at protein level)

neXtProt

NX_Q02410

Antibodypedia

APBA1 antibodies
 

PROTEIN VIEW

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APBA1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APBA1-001 ENSP00000265381
ENST00000265381
Q02410
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