DLX4

GENE INFORMATION

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Gene name

DLX4 (HGNC Symbol)

Synonyms

BP1, DLX7, DLX8, DLX9

Description

Distal-less homeobox 4 (HGNC Symbol)

Entrez gene summary

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.33

Chromosome location (bp)

48046334 - 48052321

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108813 (version 75.37)

Entrez gene

1748

UniProt

Q92988 (UniProt - Evidence at protein level)

neXtProt

NX_Q92988

Antibodypedia

DLX4 antibodies
 

PROTEIN VIEW

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DLX4-001
 
DLX4-003
 
DLX4-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DLX4-001 ENSP00000240306
ENST00000240306
Q92988
Show all »
Show » Show » 240 26.3 No 0
DLX4-003 ENSP00000410622
ENST00000411890
Q92988
Show all »
Show » Show » 168 18.9 No 0
DLX4-005 ENSP00000474516
ENST00000505318
S4R3M4
Show all »
Show » 96 10 No 0