FOLR1

GENE INFORMATION

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Gene name

FOLR1 (HGNC Symbol)

Synonyms

FOLR

Description

Folate receptor 1 (adult) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]

Chromosome

11

Cytoband

q13.4

Chromosome location (bp)

71900602 - 71907345

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000110195 (version 75.37)

Entrez gene

2348

UniProt

P15328 (UniProt - Evidence at protein level)

neXtProt

NX_P15328

Antibodypedia

FOLR1 antibodies
 

PROTEIN VIEW

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FOLR1-001
 
FOLR1-002
 
FOLR1-003
 
FOLR1-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FOLR1-001 ENSP00000308137
ENST00000312293
P15328
Show all »
Show » Show » 257 29.8 Yes 1
FOLR1-002 ENSP00000377286
ENST00000393681
P15328
Show all »
Show » Show » 257 29.8 Yes 1
FOLR1-003 ENSP00000377284
ENST00000393679
P15328
Show all »
Show » Show » 257 29.8 Yes 1
FOLR1-004 ENSP00000377281
ENST00000393676
P15328
Show all »
Show » Show » 257 29.8 Yes 1