COX7A2

GENE INFORMATION

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Gene name

COX7A2 (HGNC Symbol)

Synonyms

COX7AL, COXVIIa-L

Description

Cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (HGNC Symbol)

Entrez gene summary

Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]

Chromosome

6

Cytoband

q14.1

Chromosome location (bp)

75947391 - 75960039

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112695 (version 75.37)

Entrez gene

1347

UniProt

P14406 (UniProt - Evidence at protein level)

neXtProt

NX_P14406

Antibodypedia

COX7A2 antibodies
 

PROTEIN VIEW

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COX7A2-001
 
COX7A2-002
 
COX7A2-003
 
COX7A2-005
 
COX7A2-006
 
COX7A2-007
 
COX7A2-008
 
COX7A2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX7A2-001 ENSP00000421969
ENST00000459637
Show » 67 7.6 No 0
COX7A2-002 ENSP00000359098
ENST00000370081
H0UI06
Show all »
Show » Show » 115 12.8 No 2
COX7A2-003 ENSP00000359106
ENST00000370089
H0UI06
Show all »
Show » Show » 115 12.8 No 2
COX7A2-005 ENSP00000422979
ENST00000460985
D6R9C3
Show all »
Show » Show » 53 5.8 No 1
COX7A2-006 ENSP00000423432
ENST00000472311
D6RA35
Show all »
Show » Show » 76 9.1 No 0
COX7A2-007 ENSP00000421193
ENST00000377978
D6RGV5
Show all »
Show » Show » 103 11.5 No 0
COX7A2-008 ENSP00000425951
ENST00000509698
D6RIE3
Show all »
Show » Show » 91 10.3 No 0
COX7A2-201 ENSP00000230459
ENST00000230459
P14406
Show all »
Show » Show » 83 9.4 No 1