ITGA4

GENE INFORMATION

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Gene name

ITGA4 (HGNC Symbol)

Synonyms

CD49D

Description

Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q31.3

Chromosome location (bp)

182321929 - 182400914

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115232 (version 75.37)

Entrez gene

3676

UniProt

P13612 (UniProt - Evidence at protein level)

neXtProt

NX_P13612

Antibodypedia

ITGA4 antibodies
 

PROTEIN VIEW

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ITGA4-001
 
ITGA4-003
 
ITGA4-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITGA4-001 ENSP00000380227
ENST00000397033
P13612
Show all »
Show » Show » 1032 114.9 Yes 1
ITGA4-003 ENSP00000340149
ENST00000339307
Q7Z4L6
Show all »
Show » 195 21.5 Yes 0
ITGA4-006 ENSP00000233573
ENST00000233573
E7EP60
Show all »
Show » Show » 614 67.5 Yes 0