KLF7

GENE INFORMATION

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Gene name

KLF7 (HGNC Symbol)

Synonyms

UKLF

Description

Kruppel-like factor 7 (ubiquitous) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Chromosome

2

Cytoband

q33.3

Chromosome location (bp)

207938861 - 208031991

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000118263 (version 75.37)

Entrez gene

8609

UniProt

O75840 (UniProt - Evidence at transcript level)

neXtProt

NX_O75840

Antibodypedia

KLF7 antibodies
 

PROTEIN VIEW

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KLF7-001
 
KLF7-002
 
KLF7-003
 
KLF7-004
 
KLF7-006
 
KLF7-007
 
KLF7-008
 
KLF7-009
 
KLF7-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLF7-001 ENSP00000309570
ENST00000309446
O75840
Show all »
Show » Show » 302 33.4 No 0
KLF7-002 ENSP00000387510
ENST00000421199
O75840
Show all »
Show » Show » 269 29.6 No 0
KLF7-003 ENSP00000398572
ENST00000423015
O75840
Show all »
Show » Show » 230 24.8 No 0
KLF7-004 ENSP00000392015
ENST00000457962
E7EUU0
Show all »
Show » 60 7 No 0
KLF7-006 ENSP00000397245
ENST00000426163
E7EQY2
Show all »
Show » 112 12.8 No 0
KLF7-007 ENSP00000412950
ENST00000451244
E9PHC9
Show all »
51 6 No 0
KLF7-008 ENSP00000413590
ENST00000435602
C9JX20
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175 18.5 No 0
KLF7-009 ENSP00000393268
ENST00000458272
O75840
Show all »
Show » Show » 112 13.4 No 0
KLF7-201 ENSP00000403284
ENST00000412414
O75840
Show all »
Show » Show » 274 30.2 No 0