UBE2B

GENE INFORMATION

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Gene name

UBE2B (HGNC Symbol)

Synonyms

HHR6B, RAD6B, UBC2

Description

Ubiquitin-conjugating enzyme E2B (HGNC Symbol)

Entrez gene summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q31.1

Chromosome location (bp)

133706870 - 133727683

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000119048 (version 75.37)

Entrez gene

7320

UniProt

P63146 (UniProt - Evidence at protein level)

neXtProt

NX_P63146

Antibodypedia

UBE2B antibodies
 

PROTEIN VIEW

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UBE2B-001
 
UBE2B-004
 
UBE2B-005
 
UBE2B-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBE2B-001 ENSP00000265339
ENST00000265339
P63146
Show all »
Show » Show » 152 17.3 No 0
UBE2B-004 ENSP00000425237
ENST00000510021
D6RDW8
Show all »
Show » Show » 44 5 No 0
UBE2B-005 ENSP00000426364
ENST00000506787
H0YA80
Show all »
Show » Show » 138 15.4 No 0
UBE2B-008 ENSP00000425137
ENST00000507277
Show » Show » 141 16.1 No 0