ITIH5

GENE INFORMATION

? »

Gene name

ITIH5 (HGNC Symbol)

Synonyms

MGC10848

Description

Inter-alpha-trypsin inhibitor heavy chain family, member 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Chromosome

10

Cytoband

p14

Chromosome location (bp)

7601232 - 7708961

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000123243 (version 75.37)

Entrez gene

80760

UniProt

Q86UX2 (UniProt - Evidence at transcript level)

neXtProt

NX_Q86UX2

Antibodypedia

ITIH5 antibodies
 

PROTEIN VIEW

? »
 
 
 
ITIH5-001
 
ITIH5-003
 
ITIH5-005
 
ITIH5-201
 
ITIH5-202
 
ITIH5-203
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITIH5-001 ENSP00000256861
ENST00000256861
Q86UX2
Show all »
Show » Show » 956 106.1 Yes 0
ITIH5-003 ENSP00000298441
ENST00000298441
Q86UX2
Show all »
Show » Show » 742 82.2 No 0
ITIH5-005 ENSP00000419386
ENST00000461751
Show » 119 13.2 No 0
ITIH5-201 ENSP00000380332
ENST00000397145
G5E9D8
Show all »
Show » 702 78.4 Yes 0
ITIH5-202 ENSP00000380333
ENST00000397146
C9J2H1
Show all »
Show » 695 77.5 Yes 0
ITIH5-203 ENSP00000387969
ENST00000446830
J3KQ60
Show all »
Show » Show » 723 80 No 0