DGCR8

GENE INFORMATION

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Gene name

DGCR8 (HGNC Symbol)

Synonyms

C22orf12, DGCRK6, Gy1, pasha

Description

DGCR8 microprocessor complex subunit (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Chromosome

22

Cytoband

q11.21

Chromosome location (bp)

20067755 - 20099400

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128191 (version 75.37)

Entrez gene

54487

UniProt

Q8WYQ5 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WYQ5

Antibodypedia

DGCR8 antibodies
 

PROTEIN VIEW

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DGCR8-001
 
DGCR8-003
 
DGCR8-009
 
DGCR8-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DGCR8-001 ENSP00000263209
ENST00000351989
Q8WYQ5
Show all »
Show » Show » 773 86 No 0
DGCR8-003 ENSP00000384726
ENST00000407755
Q8WYQ5
Show all »
Show » Show » 740 82.7 No 0
DGCR8-009 ENSP00000409625
ENST00000457069
C9JSD5
Show all »
Show » 125 13.2 No 0
DGCR8-201 ENSP00000372488
ENST00000383024
Q8WYQ5
Show all »
Show » Show » 740 82.7 No 0