HOXD13

GENE INFORMATION

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Gene name

HOXD13 (HGNC Symbol)

Synonyms

HOX4I, SPD

Description

Homeobox D13 (HGNC Symbol)

Entrez gene summary

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

176957619 - 176960666

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128714 (version 75.37)

Entrez gene

3239

UniProt

P35453 (UniProt - Evidence at protein level)

neXtProt

NX_P35453

Antibodypedia

HOXD13 antibodies
 

PROTEIN VIEW

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HOXD13-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HOXD13-001 ENSP00000376322
ENST00000392539
P35453
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