DOCK6

GENE INFORMATION

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Gene name

DOCK6 (HGNC Symbol)

Synonyms

KIAA1395, ZIR1

Description

Dedicator of cytokinesis 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2. [provided by RefSeq, Dec 2011]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

11309971 - 11373157

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130158 (version 75.37)

Entrez gene

57572

UniProt

Q96HP0 (UniProt - Evidence at protein level)

neXtProt

NX_Q96HP0

Antibodypedia

DOCK6 antibodies
 

PROTEIN VIEW

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DOCK6-001
 
DOCK6-005
 
DOCK6-006
 
DOCK6-012
 
DOCK6-017
 
DOCK6-018
 
DOCK6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DOCK6-001 ENSP00000294618
ENST00000294618
Q96HP0
Show all »
Show » Show » 2047 229.6 No 0
DOCK6-005 ENSP00000467191
ENST00000590680
Show » 464 50.8 No 0
DOCK6-006 ENSP00000468638
ENST00000587656
Show » 1336 148.7 No 0
DOCK6-012 ENSP00000465767
ENST00000585904
K7EKT0
Show all »
Show » Show » 185 19.4 No 0
DOCK6-017 ENSP00000467231
ENST00000588666
Show » 148 16.7 No 0
DOCK6-018 ENSP00000468291
ENST00000587734
K7ERK2
Show all »
Show » 98 10.6 No 0
DOCK6-201 ENSP00000321556
ENST00000319867
C9IZV6
Show all »
Show » Show » 1386 154.5 No 0