PXDN

GENE INFORMATION

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Gene name

PXDN (HGNC Symbol)

Synonyms

D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN

Description

Peroxidasin homolog (Drosophila) (HGNC Symbol)

Entrez gene summary

This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis. [provided by RefSeq, Aug 2014]

Chromosome

2

Cytoband

p25.3

Chromosome location (bp)

1635659 - 1748624

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130508 (version 75.37)

Entrez gene

7837

UniProt

Q92626 (UniProt - Evidence at protein level)

neXtProt

NX_Q92626

Antibodypedia

PXDN antibodies
 

PROTEIN VIEW

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PXDN-001
 
PXDN-002
 
PXDN-006
 
PXDN-007
 
PXDN-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PXDN-001 ENSP00000252804
ENST00000252804
Q92626
Show all »
Show » Show » 1479 165.3 Yes 0
PXDN-002 ENSP00000402738
ENST00000433670
Show » Show » 723 79.8 Yes 0
PXDN-006 ENSP00000398363
ENST00000425171
C9J4I9
Show all »
Show » Show » 224 25.6 Yes 0
PXDN-007 ENSP00000408701
ENST00000447941
Show » Show » 197 22.3 No 0
PXDN-009 ENSP00000414098
ENST00000453308
Show » Show » 76 9 No 0