PPAN

GENE INFORMATION

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Gene name

PPAN (HGNC Symbol)

Synonyms

BXDC3, SSF, SSF1, SSF2

Description

Peter pan homolog (Drosophila) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation. [provided by RefSeq, Nov 2010]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

10216965 - 10225414

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130810 (version 75.37)

Entrez gene

56342

UniProt

Q9NQ55 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQ55

Antibodypedia

PPAN antibodies
 

PROTEIN VIEW

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PPAN-001
 
PPAN-002
 
PPAN-003
 
PPAN-004
 
PPAN-009
 
PPAN-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPAN-001 ENSP00000253107
ENST00000253107
Q9NQ55
Show all »
Show » Show » 473 53.2 No 0
PPAN-002 ENSP00000377382
ENST00000393793
A8MV53
Show all »
Show » 420 47.1 No 0
PPAN-003 ENSP00000410485
ENST00000446223
C9J3W3
Show all »
Show » 210 23.6 No 0
PPAN-004 ENSP00000415988
ENST00000430370
C9JHF7
Show all »
Show » 97 11 No 0
PPAN-009 ENSP00000415467
ENST00000444703
208 23.1 No 0
PPAN-201 ENSP00000450710
ENST00000556468
Q9NQ55
Show all »
Show » Show » 794 87.9 No 7