DSC1

GENE INFORMATION

? »

Gene name

DSC1 (HGNC Symbol)

Synonyms

CDHF1

Description

Desmocollin 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

q12.1

Chromosome location (bp)

28709199 - 28742819

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134765 (version 75.37)

Entrez gene

1823

UniProt

Q08554 (UniProt - Evidence at protein level)

neXtProt

NX_Q08554

Antibodypedia

DSC1 antibodies
 

PROTEIN VIEW

? »
 
 
 
DSC1-001
 
DSC1-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DSC1-001 ENSP00000257197
ENST00000257197
Q08554
Show all »
Show » Show » 840 93.8 Yes 1
DSC1-002 ENSP00000257198
ENST00000257198
Q08554
Show all »
Show » Show » 894 100 Yes 1