TMPRSS4

GENE INFORMATION

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Gene name

TMPRSS4 (HGNC Symbol)

Synonyms

MT-SP2, TMPRSS3

Description

Transmembrane protease, serine 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q23.3

Chromosome location (bp)

117947753 - 117992605

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137648 (version 75.37)

Entrez gene

56649

UniProt

Q9NRS4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9NRS4

Antibodypedia

TMPRSS4 antibodies
 

PROTEIN VIEW

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TMPRSS4-001
 
TMPRSS4-002
 
TMPRSS4-004
 
TMPRSS4-005
 
TMPRSS4-006
 
TMPRSS4-007
 
TMPRSS4-008
 
TMPRSS4-011
 
TMPRSS4-015
 
TMPRSS4-017
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TMPRSS4-001 ENSP00000435184
ENST00000534111
Q9NRS4
Show all »
Show » Show » 435 48 No 1
TMPRSS4-002 ENSP00000429889
ENST00000519236
G3V124
Show all »
Show » Show » 335 37.2 No 1
TMPRSS4-004 ENSP00000416037
ENST00000437212
Q9NRS4
Show all »
Show » Show » 437 48.2 No 1
TMPRSS4-005 ENSP00000428814
ENST00000522307
E7ESG9
Show all »
Show » Show » 290 31.8 No 0
TMPRSS4-006 ENSP00000429209
ENST00000523251
E7ERX8
Show all »
Show » Show » 397 43.8 No 0
TMPRSS4-007 ENSP00000431062
ENST00000517483
E5RJR8
Show all »
Show » 59 6.4 No 0
TMPRSS4-008 ENSP00000430547
ENST00000522824
Q9NRS4
Show all »
Show » Show » 432 47.7 No 1
TMPRSS4-011 ENSP00000428407
ENST00000522151
E5RIH1
Show all »
Show » Show » 173 19.1 No 1
TMPRSS4-015 ENSP00000429833
ENST00000517544
Show » Show » 148 16.3 No 1
TMPRSS4-017 ENSP00000428246
ENST00000524218
Show » Show » 62 7 No 0