SMAD6

GENE INFORMATION

? »

Gene name

SMAD6 (HGNC Symbol)

Synonyms

HsT17432, MADH6, MADH7

Description

SMAD family member 6 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014]

Chromosome

15

Cytoband

q22.31

Chromosome location (bp)

66994566 - 67074338

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137834 (version 75.37)

Entrez gene

4091

UniProt

O43541 (UniProt - Evidence at protein level)

neXtProt

NX_O43541

Antibodypedia

SMAD6 antibodies
 

PROTEIN VIEW

? »
 
 
 
SMAD6-001
 
SMAD6-002
 
SMAD6-003
 
SMAD6-004
 
SMAD6-201
 
SMAD6-202
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SMAD6-001 ENSP00000288840
ENST00000288840
O43541
Show all »
Show » Show » 496 53.5 No 0
SMAD6-002 ENSP00000452955
ENST00000557916
O43541
Show all »
Show » Show » 338 35.5 No 0
SMAD6-003 ENSP00000453446
ENST00000559931
H0YM33
Show all »
62 6.6 No 0
SMAD6-004 ENSP00000452694
ENST00000558937
H0YK80
Show all »
55 5.8 No 0
SMAD6-201 ENSP00000345054
ENST00000338426
O43541
Show all »
Show » Show » 235 26.2 No 0
SMAD6-202 ENSP00000396961
ENST00000457357
O43541
Show all »
Show » Show » 338 35.5 No 0