IQGAP1

GENE INFORMATION

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Gene name

IQGAP1 (HGNC Symbol)

Synonyms

HUMORFA01, KIAA0051, p195, SAR1

Description

IQ motif containing GTPase activating protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]

Chromosome

15

Cytoband

q26.1

Chromosome location (bp)

90931450 - 91045475

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000140575 (version 75.37)

Entrez gene

8826

UniProt

P46940 (UniProt - Evidence at protein level)

neXtProt

NX_P46940

Antibodypedia

IQGAP1 antibodies
 

PROTEIN VIEW

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IQGAP1-001
 
IQGAP1-004
 
IQGAP1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IQGAP1-001 ENSP00000268182
ENST00000268182
P46940
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Show » Show » 1657 189.3 No 0
IQGAP1-004 ENSP00000453181
ENST00000560738
H0YLE8
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Show » Show » 1085 124.8 No 0
IQGAP1-006 ENSP00000452723
ENST00000560418
H0YKA5
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Show » Show » 43 5 No 0