PIK3R5

TISSUE ATLAS

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Gene description

Phosphoinositide-3-kinase, regulatory subunit 5

RNA tissue category

Tissue enhanced (bone marrow).

Protein summary

Detected at High or Medium expression level in 16 of 79 analyzed normal tissue cell types.

Protein expression

Goblet cells of intestinal tract and subsets of cells in stomach showed strong cytoplasmic positivity. Strong membranous positivity was observed in renal tubules while nasopharyx showed strong cytoplasmic and membranous staining. Alveolar macrophages, gall bladder, thyroid, adrenal gland, epididymis and seminal vesicle were moderately stained. Additional luminal membranous staining was exhibited in small intestinal glands. Remaining normal tissues were generally negative.

Protein class

Disease related genes, RAS pathway related proteins

Predicted localization

Intracellular

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA052247