PPAP2C

GENE INFORMATION

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Gene name

PPAP2C (HGNC Symbol)

Synonyms

LPP2, PAP-2c

Description

Phosphatidic acid phosphatase type 2C (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

281040 - 291393

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141934 (version 75.37)

Entrez gene

8612

UniProt

O43688 (UniProt - Evidence at protein level)

neXtProt

NX_O43688

Antibodypedia

PPAP2C antibodies
 

PROTEIN VIEW

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PPAP2C-001
 
PPAP2C-003
 
PPAP2C-004
 
PPAP2C-005
 
PPAP2C-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPAP2C-001 ENSP00000269812
ENST00000269812
O43688
Show all »
Show » Show » 288 32.6 No 6
PPAP2C-003 ENSP00000388565
ENST00000434325
O43688
Show all »
Show » Show » 232 26.1 No 4
PPAP2C-004 ENSP00000329697
ENST00000327790
O43688
Show all »
Show » Show » 309 34.4 No 6
PPAP2C-005 ENSP00000466545
ENST00000591572
K7EMK9
Show all »
Show » Show » 166 18.4 Yes 2
PPAP2C-007 ENSP00000466947
ENST00000586998
Show » Show » 136 15.4 No 3