IL19

GENE INFORMATION

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Gene name

IL19 (HGNC Symbol)

Synonyms

IL-10C, IL-19, MDA1, NG.1, ZMDA1

Description

Interleukin 19 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q32.1

Chromosome location (bp)

206972215 - 207016324

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142224 (version 75.37)

Entrez gene

29949

UniProt

Q9UHD0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHD0

Antibodypedia

IL19 antibodies
 

PROTEIN VIEW

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IL19-001
 
IL19-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IL19-001 ENSP00000343000
ENST00000340758
Q9UHD0
Show all »
Show » Show » 215 24.6 No 1
IL19-002 ENSP00000270218
ENST00000270218
Q9UHD0
Show all »
Show » Show » 177 20.5 Yes 0