MARCH6

GENE INFORMATION

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Gene name

MARCH6 (HGNC Symbol)

Synonyms

MARCH-VI, RNF176, TEB4

Description

Membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of membrane-associated E3 ubiquitin ligases containing RING-CH-type zinc finger motifs. Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormone signalling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Chromosome

5

Cytoband

p15.2

Chromosome location (bp)

10353815 - 10440500

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000145495 (version 75.37)

Entrez gene

10299

UniProt

O60337 (UniProt - Evidence at protein level)

neXtProt

NX_O60337

Antibodypedia

MARCH6 antibodies
 

PROTEIN VIEW

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MARCH6-001
 
MARCH6-004
 
MARCH6-005
 
MARCH6-006
 
MARCH6-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MARCH6-001 ENSP00000274140
ENST00000274140
O60337
Show all »
Show » Show » 910 102.5 No >9
MARCH6-004 ENSP00000425930
ENST00000503788
O60337
Show all »
Show » Show » 805 90.4 No >9
MARCH6-005 ENSP00000414643
ENST00000449913
O60337
Show all »
Show » Show » 862 97.2 No >9
MARCH6-006 ENSP00000424512
ENST00000510792
Show » 608 69.2 No >9
MARCH6-007 ENSP00000426000
ENST00000502795
D6RHY7
Show all »
Show » Show » 77 9.2 No 0