NFKBIE

GENE INFORMATION

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Gene name

NFKBIE (HGNC Symbol)

Synonyms

IKBE

Description

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011]

Chromosome

6

Cytoband

p21.1

Chromosome location (bp)

44225903 - 44233500

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000146232 (version 75.37)

Entrez gene

4794

UniProt

O00221 (UniProt - Evidence at protein level)

neXtProt

NX_O00221

Antibodypedia

NFKBIE antibodies
 

PROTEIN VIEW

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NFKBIE-001
 
NFKBIE-002
 
NFKBIE-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NFKBIE-001 ENSP00000275015
ENST00000275015
O00221
Show all »
Show » Show » 500 52.9 No 0
NFKBIE-002 ENSP00000454778
ENST00000477930
Show » 224 23.7 No 0
NFKBIE-003 ENSP00000394658
ENST00000443607
H0Y4W4
Show all »
Show » Show » 55 5.9 No 0