MEPE

GENE INFORMATION

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Gene name

MEPE

Synonyms

Description

Matrix extracellular phosphoglycoprotein (HGNC Symbol)

Entrez gene summary

This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Chromosome

4

Cytoband

q22.1

Chromosome location (bp)

88742563 - 88767969

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000152595 (version 75.37)

Entrez gene

56955

UniProt

Q9NQ76 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQ76

Antibodypedia

MEPE antibodies
 

PROTEIN VIEW

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MEPE-001
 
MEPE-002
 
MEPE-003
 
MEPE-004
 
MEPE-201
 
MEPE-202
 
MEPE-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MEPE-001 ENSP00000378534
ENST00000395102
Q9NQ76
Show all »
Show » Show » 556 62.2 Yes 0
MEPE-002 ENSP00000354341
ENST00000361056
Q9NQ76
Show all »
Show » Show » 525 58.4 Yes 0
MEPE-003 ENSP00000422747
ENST00000497649
D6RAC8
Show all »
Show » 501 55.7 No 0
MEPE-004 ENSP00000421430
ENST00000511670
D6RFW6
Show all »
Show » 96 10.6 Yes 0
MEPE-201 ENSP00000416984
ENST00000424957
Q9NQ76
Show all »
Show » Show » 525 58.4 Yes 0
MEPE-202 ENSP00000443491
ENST00000540395
Q9NQ76
Show all »
Show » Show » 412 45.3 No 0
MEPE-203 ENSP00000453994
ENST00000560249
Q9NQ76
Show all »
Show » Show » 412 45.3 No 0