COX6A2

GENE INFORMATION

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Gene name

COX6A2

Synonyms

Description

Cytochrome c oxidase subunit VIa polypeptide 2 (HGNC Symbol)

Entrez gene summary

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

p11.2

Chromosome location (bp)

31439052 - 31439967

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000156885 (version 75.37)

Entrez gene

1339

UniProt

Q02221 (UniProt - Evidence at transcript level)

neXtProt

NX_Q02221

Antibodypedia

COX6A2 antibodies
 

PROTEIN VIEW

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COX6A2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX6A2-001 ENSP00000287490
ENST00000287490
Q02221
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