TRIM63

GENE INFORMATION

? »

Gene name

TRIM63 (HGNC Symbol)

Synonyms

IRF, MURF-1, RNF28, SMRZ

Description

Tripartite motif containing 63, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]

Chromosome

1

Cytoband

p36.11

Chromosome location (bp)

26377795 - 26394927

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158022 (version 75.37)

Entrez gene

84676

UniProt

Q969Q1 (UniProt - Evidence at protein level)

neXtProt

NX_Q969Q1

Antibodypedia

TRIM63 antibodies
 

PROTEIN VIEW

? »
 
 
 
TRIM63-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRIM63-001 ENSP00000363390
ENST00000374272
Q969Q1
Show all »
Show » Show » 353 40.2 No 0