LCN1

GENE INFORMATION

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Gene name

LCN1 (HGNC Symbol)

Synonyms

MGC71975, PMFA, TLC, TP, VEGP

Description

Lipocalin 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9. [provided by RefSeq, Nov 2011]

Chromosome

9

Cytoband

q34.3

Chromosome location (bp)

138413284 - 138418378

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160349 (version 75.37)

Entrez gene

3933

UniProt

P31025 (UniProt - Evidence at protein level)

neXtProt

NX_P31025

Antibodypedia

LCN1 antibodies
 

PROTEIN VIEW

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LCN1-001
 
LCN1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LCN1-001 ENSP00000263598
ENST00000263598
P31025
Show all »
Show » Show » 176 19.2 Yes 0
LCN1-002 ENSP00000360846
ENST00000371781
P31025
Show all »
Show » Show » 176 19.2 Yes 0