S100A1

GENE INFORMATION

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Gene name

S100A1 (HGNC Symbol)

Synonyms

S100-alpha, S100A

Description

S100 calcium binding protein A1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

153600402 - 153604513

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160678 (version 75.37)

Entrez gene

6271

UniProt

P23297 (UniProt - Evidence at protein level)

neXtProt

NX_P23297

Antibodypedia

S100A1 antibodies
 

PROTEIN VIEW

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S100A1-001
 
S100A1-003
 
S100A1-004
 
S100A1-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

S100A1-001 ENSP00000292169
ENST00000292169
P23297
Show all »
Show » Show » 94 10.5 No 0
S100A1-003 ENSP00000357687
ENST00000368698
Q5T7Y6
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Show » Show » 147 15.9 No 0
S100A1-004 ENSP00000389708
ENST00000436839
Q5T7Y5
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Show » Show » 34 3.8 No 0
S100A1-005 ENSP00000357685
ENST00000368696
Q5T7Y4
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Show » Show » 53 6 No 0