FBXW12

GENE INFORMATION

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Gene name

FBXW12 (HGNC Symbol)

Synonyms

Fbw12, FBXO35

Description

F-box and WD repeat domain containing 12 (HGNC Symbol)

Entrez gene summary

Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Chromosome

3

Cytoband

p21.31

Chromosome location (bp)

48413709 - 48442666

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164049 (version 75.37)

Entrez gene

285231

UniProt

Q6X9E4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q6X9E4

Antibodypedia

FBXW12 antibodies
 

PROTEIN VIEW

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FBXW12-001
 
FBXW12-002
 
FBXW12-003
 
FBXW12-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FBXW12-001 ENSP00000296438
ENST00000296438
Q6X9E4
Show all »
Show » Show » 464 53.1 No 1
FBXW12-002 ENSP00000413866
ENST00000436231
C9JK86
Show all »
Show » Show » 307 34.5 No 1
FBXW12-003 ENSP00000406139
ENST00000445170
Q6X9E4
Show all »
Show » Show » 445 50.8 No 0
FBXW12-004 ENSP00000414683
ENST00000415155
Q6X9E4
Show all »
Show » Show » 394 45 No 1