CSF2

GENE INFORMATION

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Gene name

CSF2 (HGNC Symbol)

Synonyms

GM-CSF, GMCSF

Description

Colony stimulating factor 2 (granulocyte-macrophage) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q31.1

Chromosome location (bp)

131409483 - 131411859

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164400 (version 75.37)

Entrez gene

1437

UniProt

P04141 (UniProt - Evidence at protein level)

neXtProt

NX_P04141

Antibodypedia

CSF2 antibodies
 

PROTEIN VIEW

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CSF2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CSF2-001 ENSP00000296871
ENST00000296871
P04141
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