SPAG11B

GENE INFORMATION

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Gene name

SPAG11B (HGNC Symbol)

Synonyms

EDDM2B, EP2, EP2C, EP2D, HE2

Description

Sperm associated antigen 11B (HGNC Symbol)

Entrez gene summary

This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

p23.1

Chromosome location (bp)

7300206 - 7321196

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000164871 (version 75.37)

Entrez gene

10407

UniProt

Q08648 (UniProt - Evidence at transcript level)

neXtProt

NX_Q08648

Antibodypedia

SPAG11B antibodies
 

PROTEIN VIEW

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SPAG11B-001
 
SPAG11B-002
 
SPAG11B-003
 
SPAG11B-004
 
SPAG11B-005
 
SPAG11B-006
 
SPAG11B-007
 
SPAG11B-008
 
SPAG11B-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SPAG11B-001 ENSP00000352797
ENST00000359758
E9PAK7
Show all »
Show » Show » 108 12 Yes 0
SPAG11B-002 ENSP00000354411
ENST00000361111
Show » Show » 82 9.1 Yes 0
SPAG11B-003 ENSP00000297498
ENST00000297498
Q08648
Show all »
Show » Show » 103 11.4 Yes 0
SPAG11B-004 ENSP00000322591
ENST00000317900
Q08648
Show all »
Show » Show » 113 12.7 Yes 0
SPAG11B-005 ENSP00000431230
ENST00000528168
Q08648
Show all »
Show » Show » 50 5.7 Yes 0
SPAG11B-006 ENSP00000398550
ENST00000458665
Q08648
Show all »
Show » Show » 80 9.1 Yes 0
SPAG11B-007 ENSP00000381480
ENST00000398462
A8MZA0
Show all »
Show » Show » 133 14.8 Yes 0
SPAG11B-008 ENSP00000432257
ENST00000528767
Show » 53 5.9 No 0
SPAG11B-009 ENSP00000437154
ENST00000528943
H0YF39
Show all »
Show » 106 11.8 No 0