PPIB

GENE INFORMATION

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Gene name

PPIB (HGNC Symbol)

Synonyms

CYPB, OI9

Description

Peptidylprolyl isomerase B (cyclophilin B) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]

Chromosome

15

Cytoband

q22.31

Chromosome location (bp)

64448011 - 64455404

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166794 (version 75.37)

Entrez gene

5479

UniProt

P23284 (UniProt - Evidence at protein level)

neXtProt

NX_P23284

Antibodypedia

PPIB antibodies
 

PROTEIN VIEW

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PPIB-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPIB-001 ENSP00000300026
ENST00000300026
P23284
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