SOSTDC1

GENE INFORMATION

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Gene name

SOSTDC1 (HGNC Symbol)

Synonyms

DKFZp564D206, USAG1

Description

Sclerostin domain containing 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

p21.1

Chromosome location (bp)

16501106 - 16570205

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171243 (version 75.37)

Entrez gene

25928

UniProt

Q6X4U4 (UniProt - Evidence at protein level)

neXtProt

NX_Q6X4U4

Antibodypedia

SOSTDC1 antibodies
 

PROTEIN VIEW

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SOSTDC1-001
 
SOSTDC1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SOSTDC1-001 ENSP00000304930
ENST00000307068
Q6X4U4
Show all »
Show » Show » 206 23.3 Yes 0
SOSTDC1-002 ENSP00000379889
ENST00000396652
A8MUA6
Show all »
Show » Show » 230 26.3 Yes 0