KLF11

GENE INFORMATION

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Gene name

KLF11 (HGNC Symbol)

Synonyms

MODY7, TIEG2, Tieg3

Description

Kruppel-like factor 11 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

Chromosome

2

Cytoband

p25.1

Chromosome location (bp)

10182976 - 10194963

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172059 (version 75.37)

Entrez gene

8462

UniProt

O14901 (UniProt - Evidence at protein level)

neXtProt

NX_O14901

Antibodypedia

KLF11 antibodies
 

PROTEIN VIEW

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KLF11-001
 
KLF11-002
 
KLF11-003
 
KLF11-004
 
KLF11-201
 
KLF11-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLF11-001 ENSP00000307023
ENST00000305883
O14901
Show all »
Show » Show » 512 55.1 No 0
KLF11-002 ENSP00000386058
ENST00000401510
B5MCC4
Show all »
Show » 127 13.8 No 0
KLF11-003 ENSP00000387866
ENST00000448523
E7EX78
Show all »
Show » 163 17.4 No 0
KLF11-004 ENSP00000388263
ENST00000440320
C9JM94
Show all »
Show » 122 13.3 No 0
KLF11-201 ENSP00000442722
ENST00000535335
O14901
Show all »
Show » Show » 495 53.3 No 0
KLF11-202 ENSP00000444690
ENST00000540845
O14901
Show all »
Show » Show » 495 53.3 No 0