MRP63

GENE INFORMATION

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Gene name

MRP63

Synonyms

Description

Mitochondrial ribosomal protein 63 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein which belongs to an undetermined ribosomal subunit and which seems to be specific to animal mitoribosomes. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 3p, 5q, 8q, 14q, and Y. [provided by RefSeq, Jul 2008]

Chromosome

13

Cytoband

q12.11

Chromosome location (bp)

21750784 - 21753223

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000173141 (version 75.37)

Entrez gene

78988

UniProt

Q9BQC6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BQC6

Antibodypedia

MRP63 antibodies
 

PROTEIN VIEW

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MRP63-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRP63-001 ENSP00000310726
ENST00000309594
Q9BQC6
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