WFDC5

GENE INFORMATION

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Gene name

WFDC5 (HGNC Symbol)

Synonyms

dJ211D12.5, WAP1

Description

WAP four-disulfide core domain 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q13.12

Chromosome location (bp)

43738093 - 43743813

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000175121 (version 75.37)

Entrez gene

149708

UniProt

Q8TCV5 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8TCV5

Antibodypedia

WFDC5 antibodies
 

PROTEIN VIEW

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WFDC5-001
 
WFDC5-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WFDC5-001 ENSP00000361875
ENST00000372789
Q8TCV5
Show all »
Show » Show » 123 13.3 Yes 0
WFDC5-002 ENSP00000312381
ENST00000307971
Q8TCV5
Show all »
Show » Show » 224 24.2 Yes 0