CLEC14A

GENE INFORMATION

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Gene name

CLEC14A (HGNC Symbol)

Synonyms

C14orf27

Description

C-type lectin domain family 14, member A (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012]

Chromosome

14

Cytoband

q21.1

Chromosome location (bp)

38723308 - 38725574

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000176435 (version 75.37)

Entrez gene

161198

UniProt

Q86T13 (UniProt - Evidence at protein level)

neXtProt

NX_Q86T13

Antibodypedia

CLEC14A antibodies
 

PROTEIN VIEW

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CLEC14A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLEC14A-001 ENSP00000353013
ENST00000342213
Q86T13
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