ANKLE2

GENE INFORMATION

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Gene name

ANKLE2 (HGNC Symbol)

Synonyms

KIAA0692, Lem4, LEMD7

Description

Ankyrin repeat and LEM domain containing 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the LEM family of inner nuclear membrane proteins. The encoded protein functions as a mitotic regulator through postmitotic formation of the nuclear envelope. Mutations in this gene cause morphology defects in the nuclear envelope and BAF hyperphosphorylation. [provided by RefSeq, Mar 2014]

Chromosome

12

Cytoband

q24.33

Chromosome location (bp)

133302254 - 133338474

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000176915 (version 75.37)

Entrez gene

23141

UniProt

Q86XL3 (UniProt - Evidence at protein level)

neXtProt

NX_Q86XL3

Antibodypedia

ANKLE2 antibodies
 

PROTEIN VIEW

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ANKLE2-001
 
ANKLE2-002
 
ANKLE2-003
 
ANKLE2-004
 
ANKLE2-005
 
ANKLE2-006
 
ANKLE2-008
 
ANKLE2-014
 
ANKLE2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANKLE2-001 ENSP00000350686
ENST00000357997
Q86XL3
Show all »
Show » Show » 938 104.1 No 1
ANKLE2-002 ENSP00000446268
ENST00000539605
F5H2H5
Show all »
Show » Show » 876 97.7 No 0
ANKLE2-003 ENSP00000438551
ENST00000542657
Q86XL3
Show all »
Show » Show » 293 32 No 0
ANKLE2-004 ENSP00000438515
ENST00000545623
F5H417
Show all »
Show » Show » 251 28.8 No 0
ANKLE2-005 ENSP00000445718
ENST00000546061
F5H1E7
Show all »
Show » 69 8 No 0
ANKLE2-006 ENSP00000437585
ENST00000535036
F5H6J0
Show all »
Show » 129 14.6 No 0
ANKLE2-008 ENSP00000445760
ENST00000538766
F5H1D4
Show all »
Show » 258 28.4 No 0
ANKLE2-014 ENSP00000437807
ENST00000542282
Q86XL3
Show all »
Show » Show » 293 32 No 0
ANKLE2-201 ENSP00000337651
ENST00000337516
Q86XL3
Show all »
Show » Show » 648 72.6 No 1