C8G

GENE INFORMATION

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Gene name

C8G

Synonyms

Description

Complement component 8, gamma polypeptide (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity. [provided by RefSeq, Jul 2011]

Chromosome

9

Cytoband

q34.3

Chromosome location (bp)

139839698 - 139841426

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000176919 (version 75.37)

Entrez gene

733

UniProt

P07360 (UniProt - Evidence at protein level)

neXtProt

NX_P07360

Antibodypedia

C8G antibodies
 

PROTEIN VIEW

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C8G-003
 
C8G-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

C8G-003 ENSP00000360697
ENST00000371634
Q5SQ08
Show all »
Show » Show » 164 17.6 Yes 0
C8G-004 ENSP00000224181
ENST00000224181
P07360
Show all »
Show » Show » 202 22.3 Yes 0