EDDM3B

GENE INFORMATION

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Gene name

EDDM3B (HGNC Symbol)

Synonyms

FAM12B, HE3-BETA

Description

Epididymal protein 3B (HGNC Symbol)

Entrez gene summary

Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q11.2

Chromosome location (bp)

21236586 - 21239107

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000181552 (version 75.37)

Entrez gene

64184

UniProt

P56851 (UniProt - Evidence at transcript level)

neXtProt

NX_P56851

Antibodypedia

EDDM3B antibodies
 

PROTEIN VIEW

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EDDM3B-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EDDM3B-001 ENSP00000314810
ENST00000326783
P56851
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