KRT3

GENE INFORMATION

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Gene name

KRT3 (HGNC Symbol)

Synonyms

CK3, K3

Description

Keratin 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

53183469 - 53189901

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186442 (version 75.37)

Entrez gene

3850

UniProt

P12035 (UniProt - Evidence at protein level)

neXtProt

NX_P12035

Antibodypedia

KRT3 antibodies
 

PROTEIN VIEW

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KRT3-001
 
KRT3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KRT3-001 ENSP00000413479
ENST00000417996
P12035
Show all »
Show » Show » 628 64.4 No 0
KRT3-201 ENSP00000312206
ENST00000309505
J3QST3
Show all »
Show » Show » 629 64.5 No 0