KLK12

GENE INFORMATION

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Gene name

KLK12 (HGNC Symbol)

Synonyms

KLK-L5

Description

Kallikrein-related peptidase 12 (HGNC Symbol)

Entrez gene summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.41

Chromosome location (bp)

51532348 - 51538486

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186474 (version 75.37)

Entrez gene

43849

UniProt

Q9UKR0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKR0

Antibodypedia

KLK12 antibodies
 

PROTEIN VIEW

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KLK12-001
 
KLK12-002
 
KLK12-003
 
KLK12-004
 
KLK12-005
 
KLK12-008
 
KLK12-201
 
KLK12-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLK12-001 ENSP00000434036
ENST00000529888
Q9UKR0
Show all »
Show » Show » 111 12 Yes 0
KLK12-002 ENSP00000434339
ENST00000530943
E9PPC6
Show all »
Show » 79 8.8 Yes 0
KLK12-003 ENSP00000434604
ENST00000526824
E9PPC6
Show all »
Show » 79 8.8 Yes 0
KLK12-004 ENSP00000436121
ENST00000531374
E9PR22
Show all »
Show » Show » 177 19.4 Yes 0
KLK12-005 ENSP00000436458
ENST00000525263
Q9UKR0
Show all »
Show » Show » 248 26.7 Yes 0
KLK12-008 ENSP00000250351
ENST00000250351
Q9UKR0
Show all »
Show » Show » 254 27.1 Yes 0
KLK12-201 ENSP00000250352
ENST00000250352
Q49AM7
Show all »
Show » 144 14.5 No 0
KLK12-202 ENSP00000324181
ENST00000319590
Q9UKR0
Show all »
Show » Show » 248 26.7 Yes 0