VWC2

TISSUE ATLAS

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Gene description

Von Willebrand factor C domain containing 2

RNA tissue category

Tissue enhanced (heart muscle, ovary).

Protein summary

Detected at High or Medium expression level in 21 of 77 analyzed normal tissue cell types.

Protein expression

Respiratory epithelia, hematopoietic cells, large intestine, fallopian tube and Leydig cells displayed strong cytoplasmic staining. Adrenocortical cells, glandular cells of cervix, gall bladder, renal tubules, salivary gland, thyroid and myocytes were moderately positive with additional nuclear positivity in hepatocytes. Plasma was positive. Remaining normal tissues were weakly stained or negative.

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

20
10
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA055243