TLR7

GENE INFORMATION

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Gene name

TLR7

Synonyms

Description

Toll-like receptor 7 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p22.2

Chromosome location (bp)

12885202 - 12908499

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196664 (version 75.37)

Entrez gene

51284

UniProt

Q9NYK1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NYK1

Antibodypedia

TLR7 antibodies
 

PROTEIN VIEW

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TLR7-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TLR7-001 ENSP00000370034
ENST00000380659
Q9NYK1
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