CCL3L1

GENE INFORMATION

? »

Gene name

CCL3L1 (HGNC Symbol)

Synonyms

D17S1718, G0S19-2, LD78BETA, SCYA3L, SCYA3L1

Description

Chemokine (C-C motif) ligand 3-like 1 (HGNC Symbol)

Entrez gene summary

This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Chromosome

17

Cytoband

q12

Chromosome location (bp)

34623842 - 34625731

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000205021 (version 75.37)

Entrez gene

6349

UniProt

P16619 (UniProt - Evidence at protein level)

neXtProt

NX_P16619

Antibodypedia

CCL3L1 antibodies
 

PROTEIN VIEW

? »
 
 
 
CCL3L1-001
 
CCL3L1-003
 
CCL3L1-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCL3L1-001 ENSP00000408984
ENST00000422211
P16619
Show all »
Show » Show » 93 10.2 Yes 0
CCL3L1-003 ENSP00000465806
ENST00000498676
K7EKW0
Show all »
Show » 41 4.3 Yes 0
CCL3L1-201 ENSP00000437533
ENST00000542124
A8MVB7
Show all »
Show » 47 4.9 Yes 0