VCX3B

GENE INFORMATION

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Gene name

VCX3B (HGNC Symbol)

Synonyms

VCX-C

Description

Variable charge, X-linked 3B (HGNC Symbol)

Entrez gene summary

This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22, and the Y-linked members are two identical copies of the gene within a palindromic region on chromosome Yq11. The family members share a high degree of sequence identity, with the exception that a 30-nt unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. This family member, as represented by the reference genome allele, contains 14 copies of the 30-nt repeat unit. VCX/Y genes encode small and highly charged proteins containing putative bipartite nuclear localization signals. Although the exact function of this family member has yet to be determined, a role in mRNA stability regulation can be inferred from the ability of the highly similar family member, VCX-A, to inhibit mRNA decapping. A possible role in the regulation of ribosome assembly during spermatogenesis has also been suggested. [provided by RefSeq, Aug 2010]

Chromosome

X

Cytoband

p22.31

Chromosome location (bp)

8432871 - 8434550

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000205642 (version 75.37)

Entrez gene

425054

UniProt

Q9H321 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9H321

Antibodypedia

VCX3B antibodies
 

PROTEIN VIEW

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VCX3B-001
 
VCX3B-201
 
VCX3B-202
 
VCX3B-203
 
VCX3B-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VCX3B-001 ENSP00000370420
ENST00000381032
C9JS46
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246 26.9 No 0
VCX3B-201 ENSP00000370417
ENST00000381029
B5MDK9
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214 23.3 No 0
VCX3B-202 ENSP00000410372
ENST00000440654
E7ERZ8
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186 20.1 No 0
VCX3B-203 ENSP00000414780
ENST00000444481
Q9H321
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Show » 216 23.5 No 0
VCX3B-204 ENSP00000411785
ENST00000453306
E7EUP4
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186 20 No 0