POLR2J2

GENE INFORMATION

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Gene name

POLR2J2

Synonyms

Description

DNA-directed RNA polymerase II subunit RPB11-b1 (RefSeq peptide)

Entrez gene summary

This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q22.1

Chromosome location (bp)

102277474 - 102312076

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000228049 (version 75.37)

Entrez gene

246721

UniProt

neXtProt

Antibodypedia

POLR2J2 antibodies
 

PROTEIN VIEW

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POLR2J2-002
 
POLR2J2-201
 
POLR2J2-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

POLR2J2-002 ENSP00000351218
ENST00000358438
A6NFM0
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Show » Show » 158 17.2 No 0
POLR2J2-201 ENSP00000330898
ENST00000333432
A6NJ25
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Show » Show » 116 12.7 No 0
POLR2J2-202 ENSP00000466522
ENST00000591000
F6W009
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Show » Show » 115 13.1 No 0